Preliminary Phytochemical Screening and Antimicrobial Activity of the Methanol Fractions of the Leaf of Gmelina arborea (Verbenaceae)

Leaves of Gmelina arborea are used in traditional medicine for the treatment bacterial infections without scientific validations. The main objective research was to carry out preliminary phytochemical and antimicrobial screening methanol fractions leaf arborea. extract its were screened activity using standard procedures. Preliminary revealed presence alkaloids, flavonoids, saponins, phenolic compounds, triterpenes steroids. Highest zone inhibition observed ethyl acetate fraction with (29mm) against some tested clinical pathogens compared other screened. MIC ranged between (6.25-12.5mg/ml) acetate. MBC (12.5mg/ml) This study supports folkloric claims use plant can be exploited as alternative drug infectious disease caused by these pathogens.